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KMID : 0811820140180010007
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Journal of Korean Society of Pediatric Nephrology
2014 Volume.18 No. 1 p.7 ~ p.12
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Cardiovascular Disease in Pediatric Chronic Kidney Disease
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Cho Min-Hyun
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Abstract
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Cardiovascular disease (CVD) has been identified as one of the most importantfactors influencing the long-term prognosis of patients with chronic kidneydisease (CKD). However, in pediatric CKD, the clinical importance of CVD tendsto be overlooked due to the lack of typical manifestations of CVD in this population.
The literature has identified several traditional risk factors of CVD thatoriginate from CKD, including hypertension, diabetes mellitus, dyslipidemia andobesity, in addition to new and non-traditional risk factors including anemia,secondary hyperparathyroidism, oxidative stress and inflammation. In cases ofpediatric CKD, cardiovascular disease is usually restricted to subclinical manifestationssuch as left ventricular hypertrophy, thickening of intimal media onthe carotid artery and calcification of the coronary artery. Therefore, risk factorsof CVD in pediatric CKD patients should be closely monitored.
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KEYWORD
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Cardiovascular disease, Children, Chronic kidney disease
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